Efficacy with EleviewTM

Ready-to-use ampoules premixed with methylene blue

EleviewTM is a submucosal injection agent available in convenient twist-and-go ampoules.
Eleview(tm) with methylene blue
Dr. Douglas Rex, ASGE Tech Talk:
EleviewTM Overview

Ready-to-use ampoules premixed with methylene blue

EleviewTM is a submucosal injection agent available in convenient twist-and-go ampoules.
Eleview(tm) with methylene blue

Designed for an easy and safe resection procedure1

Eleview™ is a submucosal injection agent intended for use in gastrointestinal endoscopic procedures such as polypectomy, endoscopic mucosal resection (EMR), and endoscopic submucosal dissection (ESD).
  • Provides an immediate and long-lasting cushion1 that holds for up to 45 minutes2
  • Increases visibility of target lesion margins1
  • Designed to lower the risk of gastrointestinal perforation1
  • Appropriate for challenging polyps regardless of size, location, or type
EleviewTM Procedural Demonstration
Lifts, lasts, outlasts saline2
Lifts, lasts, outlasts saline

EleviewTM vs. normal saline

Eleview™ cushion duration compared to saline
Eleview™ risks

Designed to lower risk1

EleviewTM is designed to lower the risk of gastrointestinal perforation.1
  • Helps to visualize the margins of the target lesion1
  • Improved margin visualization helps decrease risk of damage to the external muscular layer, which can lead to gastrointestinal perforation1
Time savings

Designed for efficiency

EleviewTM is designed to decrease the time needed to completely resect a lesion.3
  • Reduces reinjections required compared with saline2
  • Reduces piecemeal excisions compared with saline2
Less volume required

Requires less volume to create cushions3

EleviewTM requires less volume to create submucosal cushions compared with normal saline.3
  • Better cushion-forming ability than saline2
  • Maintains cushions without releasing liquid after resection2
  • 54% less EleviewTM is required to maintain a cushion in endoscopic submucosal dissections (ESDs)2

Methylene blue functions

Premixed into EleviewTM, methylene blue contrast agent serves key functions:
  • Provides detailed delineation of the target lesion edges throughout the resection4
  • Stains the submucosa, facilitating identification of muscle injury and enhancing the post-resection view4
Polyps
Inject to form a submucosal cushion of optimal height and duration1
Polyp resection
Reconfigures to form a colored cushion that pushes the mucosa away from the submucosa.1 Methylene blue provides detailed delineation of the lesion edges4
Polyp resection
Cushions last for up to 45 minutes,2 facilitating an easy and safe resection procedure1
Post resection view
Stains the submucosa, enhances the post-resection view, and facilitates the identification of muscle injury4

Appropriate for a range of polyp types

Eleview™ creates optimal submucosal lift for help in resecting a range of polyps, regardless of their size, location, or type.
Polyp types
Large, flat, spreading polyps
Piecemeal Endoscopic Mucosal Resection with EleviewTM
References:
1. Eleview™ Instructions for Use, Aries Pharmaceuticals, Inc. April 2017. 2. Data on File, Aries Pharmaceuticals, Inc. 3. Rex DK, Wallace M, Hassan C. A randomized, double-blind trial of a new injectable solution (SIC 8000) for endoscopic resection of large sessile polyps of the colon: an interim report. Abstract presented at: Digestive Disease Week®; May 6-9, 2017; Chicago, IL. 4. Rex DK. Twelve tips for improved EMR in the colon. Gastroenterology & Endoscopy News. February 2017(suppl).